By  Harishankar Balkrishna
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Artificial intelligence, health care, and energy transition: Three areas of focus for impact

How innovations in artificial intelligence, health care, and the energy transition can create value.

August 2024, From the Field -

Key Insights
  • Artificial intelligence (AI) can assist in reaching the targets set by the United Nations for their Sustainable Development Goals.
  • GLP‑1 drugs represent a watershed moment for the health care sector given their efficacy in treating both diabetes and obesity.
  • Energy transition extends beyond renewables, with many diverse types of companies helping in the pursuit of a net zero emissions world.

Artificial intelligence (AI), health care, and the energy transition are key areas of focus for financial markets and impact investors. AI has been a significant talking point and market driver and a defining theme for investor returns given the narrowness of equity markets. Within health care, innovations in incretins have generated considerable excitement due to their potential to reshape health care provision. Meanwhile, the renewables sector has come under increased scrutiny as higher interest rates have raised concerns around financing. Here we review some of the key dynamics for each of these sectors.

Embracing the positive sides of AI, but also being cognizant of its energy demand and equality issues

While the adoption of AI is at an early stage, it appears to be exceptionally rapid compared with previous technology booms, such as PCs and smartphones. AI is essentially software that mimics and generates human‑like responses. It can scale collective cognitive abilities, giving it the potential to provide enhancements in areas such as health care, transport, education, agriculture, and other customer‑centric experiences. Of particular interest to impact investors is the potential to explore societal and environmental implications.

"…AI can assist in reaching the targets set by the United Nations for their Sustainable Development Goals...."

Used in the correct way, AI can assist in reaching the targets set by the United Nations for their Sustainable Development Goals (UN SDGs) at a quicker pace. AI’s analytical and predictive capabilities can help in fields such as power grid optimization and reliability, while in health care, its machine learning technologies are already helping in drug discovery and improving diagnostic processes that are leading to earlier detection of diseases.

However, it’s important to monitor and evaluate the risks that can be associated with AI adoption. The sheer energy demand required to run AI data centers 24 hours a day is putting huge pressure on resources. The International Energy Agency (IEA) estimates that global data centers total electricity consumption could exceed 1,000 terawatt‑hours (TWh) by 2026, up from 460 TWh in 2022.1 Companies that help manage data center infrastructure, including cooling solutions to help handle thermal loads and power management systems, that can help data centers run more efficiently will become ever more important.

Meanwhile, worries around employment, jobs, and careers are real. We should also be concerned by the information that feeds these AI systems being created in our current societal image. The fact that AI developers tend to be men can potentially lead to gender biases in AI outputs. This is why responsible and ethical AI matters, and it’s important to understand how companies disclose that information.

Innovations in health care are leading to increased market adoption and better outcomes for patients

The World Health Organization estimates that 422 million people worldwide struggle with diabetes, which links to 1.5 million deaths per year. Obesity and other metabolic risk factors are the dominant drivers of disease globally, costing the global economy approximately 2.5% of global gross domestic product, according to the World Obesity Foundation. Recent advances, however, in GLP‑1 drugs (a type of anti‑obesity medication) represent a watershed moment for the health care sector given their efficacy in treating both diabetes and obesity. These drugs, called “agonists,” mimic the action of the body’s naturally occurring GLP‑1, a hormone produced in the gut to aid digestion and keep blood sugar in check.

At the same time, health benefits from GLP‑1s will also have a knock‑on impact to the food and beverage industry as GLP‑1 users shift their eating habits to healthier ones. Also, given GLP‑1 receptors are found in other organs, GLP‑1 drugs can have positive impact beyond diabetes and obesity. For example, early research show that these drugs can reduce alcohol cravings and early evidence suggests a role in reducing sleep apnea.

The potential longer‑term medical benefits from GLP‑1s are potentially enormous, given obesity has been identified as an upstream driver of more than 200 different diseases. But we also have to be aware of their distribution. Due to variable insurance coverage, there is potential for a widening in health inequalities. Several proof points show that greater inequalities in obesity prevalence and health outcomes are very likely a byproduct of GLP‑1 adoption. In the United States, research has found that the uptake of GLP‑1 therapies for use in treating diabetes is far reduced within the population living in socioeconomically disadvantaged areas, having low income and education levels, or belonging to racial/ethnic minorities.2 Broader distribution in time should theoretically address these inequalities, but this will require substantial engagement from employers, health care services, and pharmaceutical companies. T. Rowe Price has been engaging with producers of GLP‑1s to determine how this can be improved.

GLP-1 impacts beyond diabetes and obesity. Graphic describes that while GLP-1 receptors are concentrated in the pancreas, they are spread throughout the body, and there is evidence that GLP-A drugs can interact directly with the GLP-1 receptors in other organs. This has the potential to help with other diseases, such as liver or kidney disease, as well as helping to alleviate the symptoms of Alzheimer’s and Parkinson’s disease.

Investing in the energy transition: Beyond renewables

Investing in energy transition is more important than ever, given the urgency to keep global temperature rises below 1.5 degrees centigrade. The path to net zero,3 however, will be multidimensional given that greenhouse gas emissions come from a number of different areas (see chart). But, while decarbonization has been one of the most invested sustainability themes, some companies in the renewable energy ecosystem have faced challenges due to recent macroeconomic shifts. Supply chain disruptions, inflation, and higher interest rates have all provided headwinds for the sector.

Energy transition extends beyond renewables, however. Companies that invest in green hydrogen can help with the decarbonization of heavy industries. Precision agriculture technology that helps to improve crop productivity and reduces fertilizer use, while technologies that can limit waste in manufacturing chains, are all enablers of a net zero world.

As decarbonization of the global economy accelerates, there will also be a greater focus on what the International Labor Organization is calling “the Just Transition” in the coming years. This means greening the economy in a way that is as fair and inclusive as possible to everyone concerned, creating decent working opportunities, and leaving no one behind. This objective has the potential to generate investment opportunities in areas such as education and workforce training companies, where transitioning companies must re‑skill and up‑skill employees in new technologies. Occupational health and safety in resource‑heavy industries are also core components of a just transition, so companies that provide worker protection will come under the spotlight.

Commitments from public policies such as the Inflation Reduction Act (IRA) in the United States and the EU Just Transition Mechanism tool in Europe will help drive this dynamic. The Just Transition imperative is becoming increasingly central in the energy transition, and we expect to hear more about this theme going forward, and is a large part of our focus on “Impact Beyond the Obvious.”

The path to net zero is multidimensional

(Fig. 1) Share of global GHG emissions
Shows the share of global GHG emissions by sectors.

As of December 31, 2023.
“AFOLU” is agriculture, forestry, and other land uses. Fugitive emissions are emissions of greenhouse gases not caught by a capture system and are often due to equipment leaks, evaporative processes, and windblown disturbances.
Source: World Resources Institute, T. Rowe Price analysis.

Targeting financial returns alongside positive environmental or social impact

The backdrop for impact investing has been challenging in recent times with the power of the Magnificent Seven dominating markets and war in Europe pushing up fossil fuel prices. At the same time, the opportunity to find companies that can truly make an environmental and societal difference hasn’t waned.

"...the global opportunity set available to active investors offers exciting opportunities to invest in companies that can drive impact and financial performance."

But with the macroeconomic challenges remaining, it is important to focus on companies that can offer strong pricing power and preserve strong business moats and quality management teams that can demonstrate solid track records in capital allocation. Encouragingly, the global opportunity set available to active investors offers exciting opportunities to invest in companies that can drive impact and financial performance. From businesses that use AI to help in areas such as electrification, transportation, education, and agriculture to health care providers that use innovation to tackle diseases, we remain inspired by the continued potential to make a difference through investing in publicly listed companies.

Harishankar Balkrishna Portfolio Manager, Global Impact Equity Fund

Hari Balkrishna is a portfolio manager for the Global Impact Equity Strategy. He is a vice president of T. Rowe Price Group, Inc., and T. Rowe Price International Ltd. 

From the Field

Are GLP-1s the next industry disruptor?

Some are predicting that GLP-1s could pose a disruptive threat to the medtech industry, as demand for medical devices and surgical procedures could be greatly reduced.

1 Source: IEA, Electricity 2024—Analysis and forecast to 2026. January 2024.

2 Source: Karagiannis, T., Bekiari, E. and Tsapas, A., 2023. Socioeconomic aspects of incretin‑based therapy. Diabetologia, 66(10), pp.1859–1868.

3 Net zero refers to a state where greenhouse gas emissions into the atmosphere are balanced by removals (such as through forests or carbon capture and storage).

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Past performance is not a reliable indicator of future performance. All investments are subject to market risk, including the possible loss of principal. All charts and tables are shown for illustrative purposes only.

Risks: The fund may not succeed in generating a positive environmental and/or social impact. The fund’s incorporation of environmental and/or social impact criteria into its investment process may cause the fund to perform differently from a fund that uses a different methodology to identify and/or incorporate environmental and/or social impact criteria or relies solely or primarily on financial metrics. International investments can be riskier than U.S. investments due to the adverse effects of currency exchange rates, differences in market structure and liquidity, as well as specific country, regional, and economic developments. Investments in emerging market countries are subject to greater risk and overall volatility than investments in the U.S. and developed markets. Health sciences firms are often dependent on government funding and regulation and are vulnerable to product liability lawsuits and competition from low‑cost generic product. Investing in technology stocks entails specific risks, including the potential for wide variations in performance and usually wide price swings, up and down.

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